EORTC-24051-HNCG

Phase I/II study on induction chemotherapy followed by chemoradiation with or without lapatinib, a dual EGFR/ErbB2 kinase inhibitor, in patients with locally advanced resectable larynx and hypopharynx squamous cell.
Trial StatusAll trial activities ended
DatesDate of activation: 09-May-07
Closed on : 04-Nov-08
Data management at EORTCFull
Phase1-2
Randomized trial
Type-
Targeted Sample sizeEORTC Groups: - - All Groups: 127
Number of steps1
DrugFluorouracil
Carboplatin
Cisplatin
Docetaxel
Lapatinib
Study Staff
Type of cancerHead and Neck
Participating GroupsEORTC Head and Neck Cancer Group(Coordinating Group)
Participating centers
Protocol summaryClinicalTrials.gov
NCT numberNCT00498953
EudraCT2006-002667-33